NRF2-SHP CASCADE-MEDIATED STAT3 INACTIVATION CONTRIBUTES TO AMPK-DRIVEN PROTECTION AGAINST ENDOTOXIC INFLAMMATION

Nrf2-SHP Cascade-Mediated STAT3 Inactivation Contributes to AMPK-Driven Protection Against Endotoxic Inflammation

Signal transducer and activator of transcription 3 (STAT3) is implicated in inflammation processing, but the mechanism of its regulation mostly remains limited to Janus kinase (JAK)-mediated phosphorylation.Although AMP-activated protein kinase (AMPK)-mediated STAT3 inactivation has got documented, the molecular signaling cascade connecting STAT3 i

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Southern Bluefin Tuna Case

The Southern Bluefin Tuna Award on Jurisdiction and Admissibility of 4 August 2000 on the dispute between Australia/New Zealand and Japan became the first example of the application of compulsory arbitration under Annex VII of the 1982 UN Convention of the Law of Tool Boxes the Sea.The Arbitral Tribunal found that it did not have jurisdiction to he

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CHALLENGES OF IMPLEMENTATION OF STATE SECURITY SERVICES

In the process of managing the country, it is advisable to look at broader measures of public Tumblers administration in the implementation of specific national security services implemented to ensure existential and behavioral needs of society.The specified directory for the process to ensure the challenges of national security, will allow public

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THE EFFECT OF DIFFERENT TYPES OF PACKAGING AND STORAGE TIME ON THE QUALITY OF PETIS FROM STEAMING LIQUID MACKEREL TUNA (EUTHYNNUS AFFINIS) WITH NON-VACUUM PACKAGING METHODS

Petis is a processed product made from fish extract by the process of fermentation and is further fortified or concentrated by the addition of a helper and suction.Seeing that there are fish products that quickly suffer from a decrease in quality, therefore, there is a need for Photo Paper proper packaging and packaging methods so that they are mor

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